abstract：BACKGROUND:Visual estimation and gravimetric methods are commonly used to quantify the volume of blood loss during cesarean delivery (CD). However, the correlation between blood loss and post-CD hemoglobin (Hb) is poorly studied, and it is unclear whether the correlation varies according to how blood loss is measured. ...

journal_title：Anesthesia and analgesia

authors： Fedoruk K,Seligman KM,Carvalho B,Butwick AJ

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Prolonged continuous oxytocin administration during labor may induce oxytocin receptor desensitization, which attenuates the response of the myometrium to further oxytocin, increasing the risk of postpartum hemorrhage. The literature comparing pulsatile (intermittent) versus continuous oxytocin administratio...

journal_title：Anesthesia and analgesia

authors： Talati C,Carvalho JCA,Luca A,Balki M

更新日期：2019-04-01 00:00:00

abstract：:The brain is one of the most metabolically active organs in the body. The brain's high energy demand associated with wakefulness persists during rapid eye movement sleep, and even during non-rapid eye movement sleep, cerebral oxygen consumption is only reduced by 20%. The active bioenergetic state parallels metabolic ...

journal_title：Anesthesia and analgesia

authors： Benveniste H,Heerdt PM,Fontes M,Rothman DL,Volkow ND

更新日期：2019-04-01 00:00:00

abstract：:Heart transplantation remains the definitive management for end-stage heart failure refractory to medical therapy. While heart transplantation cases are increasing annually worldwide, there remains a deficiency in organ availability with significant patient mortality while on the waiting list. Attempts have therefore ...

journal_title：Anesthesia and analgesia

authors： Beuth J,Falter F,Pinto Ribeiro RV,Badiwala M,Meineri M

更新日期：2019-03-01 00:00:00

abstract：:Enhanced recovery after surgery (ERAS) has rapidly gained popularity in a variety of surgical subspecialities. A large body of literature suggests that ERAS leads to superior outcomes, improved patient satisfaction, reduced length of hospital stay, and cost benefits, without affecting rates of readmission after surger...

journal_title：Anesthesia and analgesia

authors： Soffin EM,Gibbons MM,Ko CY,Kates SL,Wick E,Cannesson M,Scott MJ,Wu CL

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Pro- and anti-inflammatory cytokines (adipokines) associated with adipose tissue can modulate inflammatory processes and lead to systemic inflammatory conditions such as metabolic syndrome. In the present pilot study, we investigated 3 major adipokines (leptin, adiponectin, and resistin) and 2 nonspecific pr...

journal_title：Anesthesia and analgesia

authors： Hozumi J,Sumitani M,Nishizawa D,Nagashima M,Ikeda K,Abe H,Kato R,Kusakabe Y,Yamada Y,Japanese Translational Research-Cancer Pain Research Group.

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The diagnosis of postoperative cognitive dysfunction (POCD) requires complicated neuropsychological testing and is often delayed. Possible biomarkers for early detection or prediction are essential for the prevention and treatment of POCD. Preoperative screening of salivary cortisol levels may help to identi...

journal_title：Anesthesia and analgesia

authors： Han Y,Han L,Dong MM,Sun QC,Zhang ZF,Ding K,Zhang YD,Mannan A,Xu YF,Ou-Yang CL,Li ZY,Gao C,Cao JL

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Pulmonary aspiration of gastric contents is associated with significant perioperative morbidity and mortality. Previous studies have investigated the validity, reliability, and possible clinical impact of gastric ultrasound for the assessment of gastric content at the bedside. In the present study, we examin...

journal_title：Anesthesia and analgesia

authors： Kruisselbrink R,Gharapetian A,Chaparro LE,Ami N,Richler D,Chan VWS,Perlas A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that, compared to remifentanil, dexmedetomidine used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) performed under monitored anesthesia care (MAC) in nonintubated patients would result in fewer episodes of major respiratory adverse events (number of episodes...

journal_title：Anesthesia and analgesia

authors： St-Pierre P,Tanoubi I,Verdonck O,Fortier LP,Richebé P,Côté I,Loubert C,Drolet P

更新日期：2019-01-01 00:00:00

abstract：:Informed consent for pediatric anesthesia challenges practitioners to navigate complex ethical, medical, and legal ambiguities. A patient's status as a minor does not negate the importance of his or her participation in the decision-making process but, rather, necessitates a nuanced evaluation of age and development t...

journal_title：Anesthesia and analgesia

authors： Feinstein MM,Pannunzio AE,Lobell S,Kodish E

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or small vessel cerebral arterial disease is associa...

journal_title：Anesthesia and analgesia

authors： Nomura Y,Faegle R,Hori D,Al-Qamari A,Nemeth AJ,Gottesman R,Yenokyan G,Brown C,Hogue CW

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Hypotension compromises local tissue perfusion, thereby reducing tissue oxygenation. Hypotension might thus be expected to promote infection. Hypotension on surgical wards, while usually less severe than intraoperative hypotension, is common and often prolonged. In this retrospective cohort study, we tested ...

journal_title：Anesthesia and analgesia

authors： Yilmaz HO,Babazade R,Leung S,Zimmerman NM,Makarova N,Saasouh W,Stocchi L,Gorgun E,Sessler DI,Turan A

更新日期：2018-11-01 00:00:00

abstract：:Perioperative interventions aimed at decreasing costs and improving outcomes have become increasingly popular in recent years. Anesthesiologists are often faced with a choice among different treatment strategies with little data available on the comparative cost-effectiveness. We performed a systematic review of the E...

journal_title：Anesthesia and analgesia

authors： Teja BJ,Sutherland TN,Barnett SR,Talmor DS

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO) are the leading causes of transfusion-related fatalities. While these transfusion-related pulmonary complications (TRPCs) have been well detailed in adults, their burden in pediatric subsets remains poorly de...

journal_title：Anesthesia and analgesia

authors： Thalji L,Thum D,Weister TJ,Weber WV,Stubbs JR,Kor DJ,Nemergut ME

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Thoracic aorta dissection is an acute critical condition associated with shock-induced endotheliopathy, coagulopathy, massive bleeding, and significant morbidity and mortality. Our aim was to compare the effect of coagulation support with solvent/detergent-treated pooled plasma (OctaplasLG) versus standard f...

journal_title：Anesthesia and analgesia

authors： Stensballe J,Ulrich AG,Nilsson JC,Henriksen HH,Olsen PS,Ostrowski SR,Johansson PI

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Manikins are widely used in airway management training; however, simulation of realism and interpatient variability remains a challenge. We investigated whether cadavers embalmed with the novel Fix for Life (F4L) embalmment method are a suitable and realistic model for teaching 3 basic airway skills: facemas...

journal_title：Anesthesia and analgesia

authors： van Emden MW,Geurts JJ,Schober P,Schwarte LA

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The effect of neither transfusion guidelines nor decision support tools on intraoperative transfusion has been previously evaluated. The University of Michigan introduced a transfusion guideline in 2009, and in 2011, the Department of Anesthesiology developed a transfusion decision support tool. The primary ...

journal_title：Anesthesia and analgesia

authors： Picton P,Starr J,Kheterpal S,Thompson AML,Housey M,Sathishkumar S,Dubovoy T,Kirkpatrick N,Tremper KK,Engoren M,Ramachandran SK

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:While transfusion-related acute lung injury (TRALI) remains the primary cause of transfusion-related fatalities (37%), recent reports estimate the incidence of TRALI at 0.008% per unit of plasma transfused and 0.004% per all products transfused. Because blood banks have moved toward male-predominant plasma, ...

journal_title：Anesthesia and analgesia

authors： Meyer DE,Reynolds JW,Hobbs R,Bai Y,Hartwell B,Pommerening MJ,Fox EE,Wade CE,Holcomb JB,Cotton BA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

journal_title：Anesthesia and analgesia

authors： Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices. METHODS:Patients with cirrhosi...

journal_title：Anesthesia and analgesia

authors： Quan Z,Luo C,Chi P,Wang L,He H

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The accurate measurement of oxygen consumption (VO2) and energy expenditure (EE) may be helpful to optimize the treatment of critically ill patients. However, current techniques are limited in their ability to accurately quantify these end points in infants due to a low VO2, low tidal volume, and rapid respi...

journal_title：Anesthesia and analgesia

authors： Nachman E,Clemensen P,Santos K,Cole AR,Polizzotti BD,Hofmann G,Leeman KT,van den Bosch SJ,Kheir JN

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Perioperative respiratory adverse events (PRAEs) account for the major cause of morbidity and mortality in children undergoing general anesthesia. In our institutional clinical practice, we suspected that African American children experienced untoward respiratory events more frequently than other racial grou...

journal_title：Anesthesia and analgesia

authors： Tariq S,Syed M,Martin T,Zhang X,Schmitz M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Twenty percent of patients born with congenital heart disease present with right ventricular outflow tract abnormalities. These patients require multiple surgical procedures in their lifetime. Transcatheter pulmonary valve replacement (TPVR) has become a viable alternative to conventional pulmonary valve and...

journal_title：Anesthesia and analgesia

authors： Arboleda Salazar R,Heggie J,Wolski P,Horlick E,Osten M,Meineri M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that patients with eating disorders are more likely to develop chronic pain. A misaligned diet has been reported to disrupt the sleep-awake rhythms. Combined with our previous investigation on circadian pain, we aimed to investigate the role of misaligned diet in the pain sensiti...

journal_title：Anesthesia and analgesia

authors： Xu F,Zhao X,Liu H,Shao X,Chu S,Gong X,Ma Z,Gu X

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Perioperative opioid use is associated with poor survival in patients with esophageal squamous cell carcinoma. The most common histological type of esophageal cancer in western countries is adenocarcinoma. The objective of this study was to evaluate the association between intraoperative opioid consumption a...

journal_title：Anesthesia and analgesia

authors： Du KN,Feng L,Newhouse A,Mehta J,Lasala J,Mena GE,Hofstetter WL,Cata JP

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Adverse effects of hydroxyethyl starches (HESs) have been verified in patients suffering from sepsis or kidney disease, but not in surgical patients at large. The investigation aimed to determine whether the use of HES 130/0.4 was associated with the incidence of acute postinterventional adverse events compa...

journal_title：Anesthesia and analgesia

authors： Pagel JI,Rehm M,Kammerer T,Hulde N,Speck E,Briegel J,Reinholz F,Crispin A,Hofmann-Kiefer KF

更新日期：2018-06-01 00:00:00

abstract：:Patient-reported outcomes (PROs) are measures of health status that come directly from the patient. PROs are an underutilized tool in the perioperative setting. Enhanced recovery pathways (ERPs) have primarily focused on traditional measures of health care quality such as complications and hospital length of stay. The...

journal_title：Anesthesia and analgesia

authors： Abola RE,Bennett-Guerrero E,Kent ML,Feldman LS,Fiore JF Jr,Shaw AD,Thacker JKM,Gan TJ,Miller TE,Hedrick TL,McEvoy MD,Mythen MG,Bergamaschi R,Gupta R,Holubar SD,Senagore AJ,Wischmeyer PE,Carli F,Evans DC,Guilbert S,

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Transcutaneous vagus nerve stimulation (TVNS) is a promising treatment for acute and chronic pain. However, experimental studies yielded controversial results. We examined if TVNS reduces the perceived intensity of repetitive painful heat stimulation and temporal summation of pain (TSP) in healthy volunteers...

journal_title：Anesthesia and analgesia

authors： Janner H,Klausenitz C,Gürtler N,Hahnenkamp K,Usichenko TI

更新日期：2018-06-01 00:00:00

abstract：:The pandemic of heart failure and the limited options for treatment of end-stage disease have resulted in an increase in the utilization of left ventricular assist devices (LVADs). Improvements in device technology and patient survival have led to an expanding population of patients requiring noncardiac surgery while ...

journal_title：Anesthesia and analgesia

authors： Chung M

更新日期：2018-06-01 00:00:00

abstract：:The International Standards for a Safe Practice of Anesthesia were developed on behalf of the World Federation of Societies of Anaesthesiologists (WFSA), a nonprofit organization representing anesthesiologists in 150 countries, and the World Health Organization (WHO). The recommendations have been approved by WHO and ...

journal_title：Anesthesia and analgesia

authors： Gelb AW,Morriss WW,Johnson W,Merry AF,Abayadeera A,Belîi N,Brull SJ,Chibana A,Evans F,Goddia C,Haylock-Loor C,Khan F,Leal S,Lin N,Merchant R,Newton MW,Rowles JS,Sanusi A,Wilson I,Velazquez Berumen A,International

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Postpartum depression (PPD) is associated with pain during and after delivery, with studies showing reduced rates among women delivering with labor epidural analgesia (LEA). We hypothesized that women who intend to deliver with LEA but do not receive it are at higher risk for PPD at 6 weeks due to the combin...

journal_title：Anesthesia and analgesia

authors： Orbach-Zinger S,Landau R,Harousch AB,Ovad O,Caspi L,Kornilov E,Ioscovich A,Bracco D,Davis A,Fireman S,Hoshen M,Eidelman LA

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:We evaluated the interaction of dopamine-proxymetacaine and dopamine- oxybuprocaine antinociception using isobolograms. METHODS:This experiment uses subcutaneous drug (proxymetacaine, oxybuprocaine, and dopamine) injections under the skin of the rat's back, thus simulating infiltration blocks. The dose-rela...

journal_title：Anesthesia and analgesia

authors： Chen YW,Chiu CC,Lin HT,Wang JJ,Hung CH

更新日期：2018-05-01 00:00:00

abstract：:Local anesthetics have been used clinically for more than a century, but new insights into their mechanisms of action and their interaction with biological systems continue to surprise researchers and clinicians alike. Next to their classic action on voltage-gated sodium channels, local anesthetics interact with calci...

journal_title：Anesthesia and analgesia

authors： Lirk P,Hollmann MW,Strichartz G

更新日期：2018-04-01 00:00:00

abstract：:Perioperative lung-protective ventilation (LPV) can reduce perioperative pulmonary morbidity. We hypothesized that modifying default anesthesia machine ventilator settings would increase the use of intraoperative LPV. Default tidal volume settings on our anesthesia machines were decreased from 600 to 400 mL, and defau...

journal_title：Anesthesia and analgesia

authors： Chiao SS,Colquhoun DA,Naik BI,Ma JZ,Nemergut EC,Durieux ME,Blank RS,Forkin KT

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The relatively short duration of effect of local anesthetics has been addressed by encapsulation in drug delivery systems. Codelivery with a single compound that produces an adjuvant effect on nerve block but without intrinsic local anesthetic properties can further prolong the nerve block effect. Here, we i...

journal_title：Anesthesia and analgesia

authors： Rwei AY,Sherburne RT,Zurakowski D,Wang B,Kohane DS

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine a set of timing, shape, and statistical features available through noninvasive monitoring of maternal electrocardiogram and photoplethysmography that identifies preeclamptic patients. METHODS:Pregnant women admitted to Labor and Delivery were monitored with pulse oxim...

journal_title：Anesthesia and analgesia

authors： Euliano TY,Michalopoulos K,Singh S,Gregg AR,Del Rio M,Vasilopoulos T,Johnson AM,Onkala A,Darmanjian S,Euliano NR,Ho M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Early hyperglycemia is associated with multiple organ failure (MOF) after traumatic injury; however, few studies have considered the contribution of depth of clinical shock. We hypothesize that when considered simultaneously, glucose and lactate are associated with MOF in severely injured blunt trauma patien...

journal_title：Anesthesia and analgesia

authors： Richards JE,Scalea TM,Mazzeffi MA,Rock P,Galvagno SM Jr

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The US Food and Drug Administration (FDA) conducts inspections of clinical investigation sites as a component of clinical trial regulation. The FDA describes the results of these inspections in the Clinical Investigator Inspection List (CLIIL). More serious violations are followed up in FDA warning letters i...

journal_title：Anesthesia and analgesia

authors： Romano CA,Nair S,Delphin ES

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Preoperative risk stratification is a critical element in assessing the risks and benefits of surgery. Prior work has demonstrated that intra-abdominal general surgery patients can be classified based on their comorbidities and risk factors using latent class analysis (LCA), a model-based clustering techniqu...

journal_title：Anesthesia and analgesia

authors： Kim M,Wall MM,Li G

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The Chinese health care system must meet the needs of 19% of the world's population. Despite recent economic growth, health care resources are unevenly distributed. This creates the potential for job stress and burnout. We therefore conducted a survey among anesthesiologists in the Beijing-Tianjin-Hebei regi...

journal_title：Anesthesia and analgesia

authors： Li H,Zuo M,Gelb AW,Zhang B,Zhao X,Yao D,Xia D,Huang Y

更新日期：2018-03-01 00:00:00